Stillbirth risk on fat-1 transgenic foetus of sheep caused by deregulated DNA methylation of imprinted genes

Imprinted genes play important roles on embryonic development. Aiming at the stillbirths in fat-1 transgenic foetuses of sheep, we detected the DNA methylation levels of candidate CpG regions in five imprinted genes (h19, igf2, igf2r, dlk1 and gtl2) of diverse tissues in the sheep foetuses, includin...

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Bibliographic Details
Main Authors: Yu Cao, Zhicheng Dong, Dong Zhang, Huanmin Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Applied Animal Research
Subjects:
Online Access:http://dx.doi.org/10.1080/09712119.2019.1575224