An increase in the cerebral infarction area during fatigue is mediated by il-6 through an induction of fibrinogen synthesis

OBJECTIVES:Our study aimed to investigate the impact of fatigue on the severity of stroke and to explore the underlying mechanisms.METHODS:Fatigued male rats underwent middle cerebral artery occlusion and the infarcted brain area was determined. Then, coagulation parameters were assessed in the fati...

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Bibliographic Details
Main Authors: Hong Lei, Jian Xu, Li-Juan Cheng, Qi Guo, An-Mei Deng, Yong-Shen Li
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2014-06-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000600426&lng=en&tlng=en