Optimizing the phenotyping of rodent ASD models: enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features

Optimizing the phenotyping of rodent ASD models: enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features

<p>Abstract</p> <p>Background</p> <p>There is interest in defining mouse neurobiological phenotypes useful for studying autism spectrum disorders (ASD) in both forward and reverse genetic approaches. A recurrent focus has been on high-order behavioral analyses, includin...

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Bibliographic Details
Main Authors: Buxbaum Joseph D, Betancur Catalina, Bozdagi Ozlem, Dorr Nate P, Elder Gregory A, Hof Patrick R
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Molecular Autism
Subjects:
Systems biology
mouse behavior
autism
autism spectrum disorders
genetically modified mice
forward genetics
reverse genetics
Online Access:http://www.molecularautism.com/content/3/1/1

Internet

http://www.molecularautism.com/content/3/1/1

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