The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice.

African trypanosomes are extracellular parasitic protozoa, predominantly transmitted by the bite of the haematophagic tsetse fly. The main mechanism considered to mediate parasitemia control in a mammalian host is the continuous interaction between antibodies and the parasite surface, covered by var...

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Bibliographic Details
Main Authors: Stefan Magez, Anita Schwegmann, Robert Atkinson, Filip Claes, Michael Drennan, Patrick De Baetselier, Frank Brombacher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2483930?pdf=render