Genotype 1 hepatitis C virus envelope features that determine antiviral response assessed through optimal covariance networks.

Genotype 1 hepatitis C virus envelope features that determine antiviral response assessed through optimal covariance networks.

The poor response to the combined antiviral therapy of pegylated alfa-interferon and ribavarin for hepatitis C virus (HCV) infection may be linked to mutations in the viral envelope gene E1E2 (env), which can result in escape from the immune response and higher efficacy of viral entry. Mutations tha...

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Bibliographic Details
Main Authors: John M Murray, Rémy Moenne-Loccoz, Aurélie Velay, François Habersetzer, Michel Doffoël, Jean-Pierre Gut, Isabel Fofana, Mirjam B Zeisel, Françoise Stoll-Keller, Thomas F Baumert, Evelyne Schvoerer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688619?pdf=render

Internet

http://europepmc.org/articles/PMC3688619?pdf=render

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