Diversity in responses to oncolytic Lassa-vesicular stomatitis virus in patient-derived glioblastoma cells

Diversity in responses to oncolytic Lassa-vesicular stomatitis virus in patient-derived glioblastoma cells

The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using established glioblastoma cell lines. These experiments were...

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Bibliographic Details
Main Authors: Teddy E. Kim, Shelby Puckett, Kailong Zhang, Denise M. Herpai, David A. Ornelles, John N. Davis, Anthony N. van den Pol, Waldemar Debinski, Douglas S. Lyles
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
glioblastoma
vesicular stomatitis virus
GBM subtypes
interferon pathway
glioma stem-like cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770521000826

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http://www.sciencedirect.com/science/article/pii/S2372770521000826

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