In silco studies on modified hydroxamic acid and valporic acid as potential inhibitors for HDAC2

Histone deacetylases2, Class 1 HDAC family are emerged as an important therapeutic target for the treatment of various cancers. HDAC2 inhibitors are potent anti-cancer agents. Two inhibitors of HDAC2 are Hydroxamic acid and Valporic acid which are potent inducers of growth arrest, differentiation, a...

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Bibliographic Details
Main Authors: Naresh Kandakatla, Shikha Rathaur, Smruti Sandhya Sahoo, Geetha Ramakrishnan
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2013-08-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:http://www.banglajol.info/bd/index.php/BJP/article/view/15433