The bifunctional dihydrofolate reductase thymidylate synthase of <it>Tetrahymena thermophila </it>provides a tool for molecular and biotechnology applications

<p>Abstract</p> <p>Background</p> <p>Dihydrofolate reductase (DHFR) and thymidylate synthase (TS) are crucial enzymes in DNA synthesis. In alveolata both enzymes are expressed as one bifunctional enzyme.</p> <p>Results</p> <p>Loss of this essenti...

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Bibliographic Details
Main Authors: Tiedtke Arno, Bockau Ulrike, Herrmann Lutz, Hartmann Marcus WW, Weide Thomas
Format: Article
Language:English
Published: BMC 2006-03-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/6/21