Exogenous 10 kDa-Heat Shock Protein Preserves Mitochondrial Function After Hypoxia/Reoxygenation

Exogenous 10 kDa-Heat Shock Protein Preserves Mitochondrial Function After Hypoxia/Reoxygenation

Humoral factors released during ischemic preconditioning (IPC) protect the myocardium against ischemia/reperfusion (I/R) injury. We have recently identified 10 kDa-heat shock protein (HSP10) and a fraction of small 5–10 kDa peptides (5–10-sP) in the coronary effluent of IPC-treated hearts and demons...

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Bibliographic Details
Main Authors: Leonardo Maciel, Dahienne Ferreira de Oliveira, Gustavo Monnerat, Antonio Carlos Campos de Carvalho, Jose Hamilton Matheus Nascimento
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
ischemic preconditioning
mitochondria
HSP10
humoral factors
cardioprotection
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00545/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00545/full

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