Genetic variants of MICB and PLCE1 and associations with non-severe dengue.

Genetic variants of MICB and PLCE1 and associations with non-severe dengue.

A recent genome-wide association study (GWAS) identified susceptibility loci for dengue shock syndrome (DSS) at MICB rs3132468 and PLCE1 rs3740360. The aim of this study was to define the extent to which MICB (rs3132468) and PLCE1 (rs3740360) were associated with less severe clinical phenotypes of p...

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Bibliographic Details
Main Authors: James Whitehorn, Tran Nguyen Bich Chau, Nguyen Minh Nguyet, Duong Thi Hue Kien, Nguyen Than Ha Quyen, Dinh The Trung, Junxiong Pang, Bridget Wills, Nguyen Van Vinh Chau, Jeremy Farrar, Martin L Hibberd, Chiea Chuen Khor, Cameron P Simmons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3594159?pdf=render

Internet

http://europepmc.org/articles/PMC3594159?pdf=render

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