Enantioselective reduction of ketoimines promoted by easily available (S)-proline derivatives

The behavior of readily synthesized and even commercially available (S)-proline derivatives, was studied in the trichlorosilane-mediated reduction of ketoimines. A small library of structurally and electronically modified chiral Lewis bases was considered; such compounds were shown to promote the en...

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Bibliographic Details
Main Authors: Martina Bonsignore, Maurizio Benaglia, Laura Raimondi, Manuel Orlandi, Giuseppe Celentano
Format: Article
Language:English
Published: Beilstein-Institut 2013-04-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.9.71