In vitro gentamicin exposure alters caveolae protein profile in cochlear spiral ligament pericytes

In vitro gentamicin exposure alters caveolae protein profile in cochlear spiral ligament pericytes

Abstract Background The aminoglycoside antibiotic gentamicin is an ototoxic drug and has been used experimentally to investigate cochlear damage induced by noise. We have investigated the changes in the protein profile associated with caveolae in gentamicin treated and untreated spiral ligament (SL)...

Full description

Bibliographic Details
Main Authors: Elisa Ghelfi, Yohann Grondin, Emil J. Millet, Adam Bartos, Magda Bortoni, Clara Oliveira Gomes dos Santos, Humberto J. Trevino-Villarreal, Rosalinda Sepulveda, Rick Rogers
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Proteome Science
Subjects:
Ototoxic drug
Nonsyndromic hearing loss
Rab GTPase
GOrilla enrichment analysis
Proteomaps
Online Access:http://link.springer.com/article/10.1186/s12953-018-0132-x

Internet

http://link.springer.com/article/10.1186/s12953-018-0132-x

Similar Items