Paroxysmal nocturnal hemoglobinuria: rare cause of acute renal failure
Paroxysmal nocturnal hemoglobinuria is a rare acquired disease, characterized by hemolytic anemia, recurrent infections, cytopenias, and vascular thrombosis. It occurs by non-malignant clonal expansion of one or more hematopoietic stem cells that acquired somatic mutations in PIG-A gene linked to ch...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
University of São Paulo
2012-12-01
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Series: | Autopsy and Case Reports |
Subjects: | |
Online Access: | http://www.revistas.usp.br/autopsy/article/view/48368 |