Paroxysmal nocturnal hemoglobinuria: rare cause of acute renal failure

Paroxysmal nocturnal hemoglobinuria: rare cause of acute renal failure

Paroxysmal nocturnal hemoglobinuria is a rare acquired disease, characterized by hemolytic anemia, recurrent infections, cytopenias, and vascular thrombosis. It occurs by non-malignant clonal expansion of one or more hematopoietic stem cells that acquired somatic mutations in PIG-A gene linked to ch...

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Bibliographic Details
Main Authors: Vilma Takayasu, Márcia Yoshie Kanegae, Jairo Rays
Format: Article
Language:English
Published: University of São Paulo 2012-12-01
Series:Autopsy and Case Reports
Subjects:
Hemoglobinuria
Paroxysmal
Anemia
Hemolytic
Acute kidney injury
Flow cytometry
Online Access:http://www.revistas.usp.br/autopsy/article/view/48368

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