Establishment of a reverse genetics system for SARS-CoV-2 using circular polymerase extension reaction

Establishment of a reverse genetics system for SARS-CoV-2 using circular polymerase extension reaction

Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been identified as the causative agent of coronavirus disease 2019 (COVID-19). Although multiple mutations have been observed in SARS-CoV-2, functional analysis of each mutation of SARS-CoV-2 has been limited by the lack of co...

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Bibliographic Details
Main Authors: Shiho Torii, Chikako Ono, Rigel Suzuki, Yuhei Morioka, Itsuki Anzai, Yuzy Fauzyah, Yusuke Maeda, Wataru Kamitani, Takasuke Fukuhara, Yoshiharu Matsuura
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports
Subjects:
SARS-CoV-2
reverse genetics
infectious clone
CPER
mutagenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721003284

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http://www.sciencedirect.com/science/article/pii/S2211124721003284

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