Fluorescence derivatization of clarithromycin for high performance liquid chromatographic determination with fluorescence detection
Clarithromycin (CAM) is a semisynthetic macrolide antibiotic whose chemical structure has no suitable chromophore for highly sensitive and accurate direct determination. The aim of this study was toderivatize CAM with fluorescence-labeling compounds capable of enhancing the sensitivity of CAM determ...
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| Format: | Article |
| Language: | English |
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Prince of Songkla University
2007-03-01
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| Series: | Songklanakarin Journal of Science and Technology (SJST) |
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| Online Access: | http://www.sjst.psu.ac.th/journal/29_2_pdf/17clarithromycin_427-440.pdf |