Utilizing genotype imputation for the augmentation of sequence data.

In recent years, capabilities for genotyping large sets of single nucleotide polymorphisms (SNPs) has increased considerably with the ability to genotype over 1 million SNP markers across the genome. This advancement in technology has led to an increase in the number of genome-wide association studi...

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Bibliographic Details
Main Authors: Brooke L Fridley, Gregory Jenkins, Matthew E Deyo-Svendsen, Scott Hebbring, Robert Freimuth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2882389?pdf=render