Modular mimicry and engagement of the Hippo pathway by Marburg virus VP40: Implications for filovirus biology and budding.

Ebola (EBOV) and Marburg (MARV) are members of the Filoviridae family, which continue to emerge and cause sporadic outbreaks of hemorrhagic fever with high mortality rates. Filoviruses utilize their VP40 matrix protein to drive virion assembly and budding, in part, by recruitment of specific WW-doma...

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Main Authors: Ziying Han, Shantoshini Dash, Cari A Sagum, Gordon Ruthel, Chaitanya K Jaladanki, Corbett T Berry, Michael P Schwoerer, Nina M Harty, Bruce D Freedman, Mark T Bedford, Hao Fan, Sachdev S Sidhu, Marius Sudol, Olena Shtanko, Ronald N Harty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008231