Phenylethanoid Glycosides From Callicarpa kwangtungensis Chun Attenuate TNF-α-Induced Cell Damage by Inhibiting NF-κB Pathway and Enhancing Nrf2 Pathway in A549 Cells

Phenylethanoid Glycosides From Callicarpa kwangtungensis Chun Attenuate TNF-α-Induced Cell Damage by Inhibiting NF-κB Pathway and Enhancing Nrf2 Pathway in A549 Cells

Background: Acute lung injury (ALI) is a complicated and severe lung disease, which is often characterized by acute inflammation. Poliumoside (POL), acteoside (ACT) and forsythiaside B (FTB) are phenylethanoid glycosides (PGs) with strong antioxidant, anti-inflammatory, and anti-apoptotic properties...

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Bibliographic Details
Main Authors: Jing-Na Zheng, Jian-Yi Zhuo, Juan Nie, Yan-Lu Liu, Bao-Yi Chen, Ai-Zhi Wu, Yu-Cui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
acute lung injury
callicarpa kwangtungensis chun
TNF-α
NF-κB
Nrf2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.693983/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.693983/full

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