3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders

3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders

Abstract Three-dimensional (3D) brain organoids derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), appear to recapitulate the brain’s 3D cytoarchitectural arrangement and provide new opportunities to explore disease pa...

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Bibliographic Details
Main Authors: Chun-Ting Lee, Raphael M. Bendriem, Wells W. Wu, Rong-Fong Shen
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Journal of Biomedical Science
Subjects:
3D brain organoids
Induced pluripotent stem cells
Brain development
Neocortex
Neurodevelopmental disorder
Neurodegenerative disorder
Online Access:http://link.springer.com/article/10.1186/s12929-017-0362-8

Internet

http://link.springer.com/article/10.1186/s12929-017-0362-8

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