Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis.
The complex interactions between recurrent trypsin-mediated pancreatic injury, alcohol-associated pancreatic injury and SPINK1 polymorphisms in chronic pancreatitis (CP) are undefined. We hypothesize that CP occurs as a result of multiple pathological mechanisms (pathways) that are initiated by diff...
Main Authors: | Elie Aoun, Chung-Chou H Chang, Julia B Greer, Georgios I Papachristou, M Michael Barmada, David C Whitcomb |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-04-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2289874?pdf=render |
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