A standardized polyherbal preparation POL-6 diminishes alcohol withdrawal anxiety by regulating Gabra1, Gabra2, Gabra3, Gabra4, Gabra5 gene expression of GABAA receptor signaling pathway in rats

A standardized polyherbal preparation POL-6 diminishes alcohol withdrawal anxiety by regulating Gabra1, Gabra2, Gabra3, Gabra4, Gabra5 gene expression of GABAA receptor signaling pathway in rats

Abstract Background Alcohol abuse is a major problem worldwide and it affects people’s health and economy. There is a relapse in alcohol intake due to alcohol withdrawal. Alcohol withdrawal anxiety-like behavior is a symptom that appears 6–24 h after the last alcohol ingestion. Methods The present s...

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Bibliographic Details
Main Authors: Lalit Sharma, Aditi Sharma, Ashutosh Kumar Dash, Gopal Singh Bisht, Girdhari Lal Gupta
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Polyherbal preparation
Alcohol withdrawal
Anxiety
GABAA receptor
Gene expression
Online Access:https://doi.org/10.1186/s12906-020-03181-2

Internet

https://doi.org/10.1186/s12906-020-03181-2

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