Phenol-Soluble Modulin α Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent Pathway

Neutrophils have the ability to capture and kill microbes extracellularly through the formation of neutrophil extracellular traps (NETs). These are DNA and protein structures that neutrophils release extracellularly and are believed to function as a defense mechanism against microbes. The classic NE...

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Bibliographic Details
Main Authors: Halla Björnsdottir, Agnes Dahlstrand Rudin, Felix P. Klose, Jonas Elmwall, Amanda Welin, Marios Stylianou, Karin Christenson, Constantin F. Urban, Huamei Forsman, Claes Dahlgren, Anna Karlsson, Johan Bylund
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-03-01
Series:Frontiers in Immunology
Subjects:
PSM
ROS
MPO
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00257/full