Biogenesis and proteolytic processing of lysosomal DNase II.

Biogenesis and proteolytic processing of lysosomal DNase II.

Deoxyribonuclease II (DNase II) is a key enzyme in the phagocytic digestion of DNA from apoptotic nuclei. To understand the molecular properties of DNase II, particularly the processing, we prepared a polyclonal antibody against carboxyl-terminal sequences of mouse DNase II. In the present study, pa...

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Bibliographic Details
Main Authors: Susumu Ohkouchi, Masahiro Shibata, Mitsuho Sasaki, Masato Koike, Paul Safig, Christoph Peters, Shigekazu Nagata, Yasuo Uchiyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3596287?pdf=render

Internet

http://europepmc.org/articles/PMC3596287?pdf=render

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