Effects of α-tocopherol on hemolysis and oxidative stress markers on red blood cells in β-thalassemia major

Effects of α-tocopherol on hemolysis and oxidative stress markers on red blood cells in β-thalassemia major

Background The accumulation of unpaired α-globin chains in patients with β-thalassemia major may clinically create ineffective erythropoiesis, hemolysis, and chronic anemia. Multiple blood transfusions and iron overload cause cellular oxidative damage. However, α-tocopherol, an antioxidant, is a pot...

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Bibliographic Details
Main Authors: Nora Sovira, Munar Lubis, Pustika Amalia Wahidiyat, Franciscus D. Suyatna, Djajadiman Gatot, Saptawati Bardosono, Mohammad Sadikin
Format: Article
Language:English
Published: The Korean Pediatric Society 2020-08-01
Series:Clinical and Experimental Pediatrics
Subjects:
α-tocopherol
hemolysis
oxidative stress
β-thalassemia major
Online Access:http://www.e-cep.org/upload/pdf/cep-2019-00542.pdf

Internet

http://www.e-cep.org/upload/pdf/cep-2019-00542.pdf

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