Minocycline Attenuates Stress-Induced Behavioral Changes via Its Anti-inflammatory Effects in an Animal Model of Post-traumatic Stress Disorder

Minocycline Attenuates Stress-Induced Behavioral Changes via Its Anti-inflammatory Effects in an Animal Model of Post-traumatic Stress Disorder

Accumulating evidences have suggested that anxiety-like behavior and impairment of learning and memory are key symptoms of post-traumatic stress disorder (PTSD), and pharmacological treatment can ameliorate anxiety and cognitive impairments. Recent studies have shown that minocycline exhibits anxiol...

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Bibliographic Details
Main Authors: Wei Wang, Rui Wang, Jingjing Xu, Xiaqing Qin, Hong Jiang, Arslan Khalid, Dexiang Liu, Fang Pan, Cyrus S. H. Ho, Roger C. M. Ho
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Psychiatry
Subjects:
post-traumatic stress disorder
inescapable foot shock
microglia
minocycline
pro-inflammatory cytokines
NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00558/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2018.00558/full

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