Gut Microbiota Combined With Metabolomics Reveals the Repeated Dose Oral Toxicity of β-Cyclodextrin in Mice

Gut Microbiota Combined With Metabolomics Reveals the Repeated Dose Oral Toxicity of β-Cyclodextrin in Mice

Βeta-cyclodextrin (β-CD) with a hydrophobic cavity enables the formation of inclusion complexes with organic molecules. The formation of host–guest complexes makes the application of β-CD popular in many fields, but their interaction with organisms is poorly understood. In the present study, the eff...

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Bibliographic Details
Main Authors: Shuangyu Lv, Xiaomei Zhang, Yu Feng, Qiying Jiang, Chenguang Niu, Yanjie Yang, Xinchun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
β-cyclodextrin
gut microbiota
metabolomics
oral exposure
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.574607/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.574607/full

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