Preclinical Safety Evaluation of Ophthalmic Viscosurgical Devices in Rabbits and a Novel Mini-Pig Model

Abstract Introduction To establish the preclinical safety and equivalency of ophthalmic viscosurgical devices (OVDs) comprised of bacterially sourced sodium hyaluronate (HA) to animal sourced HA using pyrogenicity and aqueous exchange models in rabbits and a novel mini-pig model to evaluate corneal...

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Bibliographic Details
Main Authors: Ronika S. Leang, Lisa J. Kloft, Brad Gray, Arlene E. Gwon, Ling C. Huang
Format: Article
Language:English
Published: Adis, Springer Healthcare 2019-02-01
Series:Ophthalmology and Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1007/s40123-019-0167-9