Mesenchymal Stromal Cell-Derived Microvesicles Regulate an Internal Pro-Inflammatory Program in Activated Macrophages

Mesenchymal Stromal Cell-Derived Microvesicles Regulate an Internal Pro-Inflammatory Program in Activated Macrophages

Mesenchymal stromal cells (MSCs) are multipotent cells with abilities to exert immunosuppressive response promoting tissue repair. Studies have shown that MSCs can secrete extracellular vesicles (MVs-MSCs) with similar regulatory functions to the parental cells. Furthermore, strong evidence suggesti...

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Bibliographic Details
Main Authors: Juan S. Henao Agudelo, Tarcio T. Braga, Mariane T. Amano, Marcos A. Cenedeze, Regiane A. Cavinato, Amandda R. Peixoto-Santos, Marcelo N. Muscará, Simone A. Teixeira, Mario C. Cruz, Angela Castoldi, Rita Sinigaglia-Coimbra, Alvaro Pacheco-Silva, Danilo C. de Almeida, Niels Olsen Saraiva Camara
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
mesenchymal stromal cells
microvesicles
macrophages
immunomodulation
acute peritonitis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00881/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00881/full

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