The Role of New Technologies in Myeloproliferative Neoplasms

The Role of New Technologies in Myeloproliferative Neoplasms

The hallmark of BCR-ABL1-negative myeloproliferative neoplasms (MPNs) is the presence of a driver mutation in JAK2, CALR, or MPL gene. These genetic alterations represent a key feature, useful for diagnostic, prognostic and therapeutical approaches. Molecular biology tests are now widely available w...

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Bibliographic Details
Main Authors: Giuseppe A. Palumbo, Stefania Stella, Maria Stella Pennisi, Cristina Pirosa, Elisa Fermo, Sonia Fabris, Daniele Cattaneo, Alessandra Iurlo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
BCR-ABL1-negative myeloproliferative neoplasms (MPNs)
myelofibrosis (MF)
JAK2 mutations
calreticulin (CALR)
MPL (W515K/L)
ASXL1 mutation
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00321/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00321/full

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