Molecular evolution and the role of oxidative stress in the expansion and functional diversification of cytosolic glutathione transferases

<p>Abstract</p> <p>Background</p> <p>Cytosolic glutathione transferases (cGST) are a large group of ubiquitous enzymes involved in detoxification and are well known for their undesired side effects during chemotherapy. In this work we have performed thorough phylogeneti...

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Bibliographic Details
Main Authors: Vasconcelos Vítor, O'Brien Stephen J, Johnson Warren E, da Fonseca Rute R, Antunes Agostinho
Format: Article
Language:English
Published: BMC 2010-09-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/10/281