LC-MS/MS assay of riluzole and etoricoxib in rat plasma and brain tissue with applications for sampling and evaluation in pre-clinical rat model of traumatic brain injury
A sensitive and robust liquid chromatography – tandem mass spectrometry (LC-MS/MS) method was developed and validated to simultaneously quantify the concentration levels of selective cyclo-oxygenase- 2 inhibitor, etoricoxib, and glutamate antagonist, riluzole, in rat plasma and brain tissue. Labeled...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-12-01
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| Series: | Talanta Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666831921000229 |