Royal jelly attenuates metabolic defects in a Drosophila mutant with elevated TORC1 activity

Target of rapamycin complex 1 (TORC1) is a master regulator of cell metabolism, and its dysregulation has been linked to an array of pathologies, including cancer and age-related diseases. Nprl3, a component of GTPase-activating protein towards Rags complex 1 (GATOR1), inhibits TORC1 activity under...

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Bibliographic Details
Main Authors: Yang Cheng, Jiadong Cai, Yuanyuan Fu, Congjing Feng, Yue Hao, Youheng Wei
Format: Article
Language:English
Published: The Company of Biologists 2020-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/9/11/bio054999