Topics on the Na+/Ca2+ Exchanger: Pharmacological Characterization of Na+/Ca2+ Exchanger Inhibitors

Using the whole-cell voltage clamp, we examined acute effects of various agents on Na+/Ca2+ exchange current (INCX) in guinea-pig cardiac ventricular cells and transfected cells. Among the antiarrhythmic drugs, amiodarone, bepridil, dronedarone, cibenzoline, azimilide, and aprindine inhibited INCX i...

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Bibliographic Details
Main Authors: Yasuhide Watanabe, Yuuki Koide, Junko Kimura
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344093