Surfactant lipids regulate LPS-induced interleukin-8 production in A549 lung epithelial cells by inhibiting translocation of TLR4 into lipid raft domains

In addition to providing mechanical stability, growing evidence suggests that surfactant lipid components can modulate inflammatory responses in the lung. However, little is known of the molecular mechanisms involved in the immunomodulatory action of surfactant lipids. This study investigates the ef...

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Bibliographic Details
Main Authors: Wondwossen Abate, Abdulaziz A. Alghaithy, Joan Parton, Kenneth P. Jones, Simon K. Jackson
Format: Article
Language:English
Published: Elsevier 2010-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520305381