Molecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts

Molecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts

Synthetic cathinones are popular psychoactive substances that may cause skeletal muscle damage. In addition to indirect sympathomimetic myotoxicity, these substances could be directly myotoxic. Since studies in myocytes are currently lacking, the aim of the present study was to investigate potential...

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Bibliographic Details
Main Authors: Xun Zhou, Dino Luethi, Gerda M. Sanvee, Jamal Bouitbir, Matthias E. Liechti, Stephan Krähenbühl
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
synthetic cathinones
skeletal muscle toxicity
mitochondria
electron transport chain
Online Access:https://www.mdpi.com/1422-0067/20/7/1561

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https://www.mdpi.com/1422-0067/20/7/1561

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