HLA-dependent heterogeneity and macrophage immunoproteasome activation during lung COVID-19 disease
Abstract Background The worldwide pandemic caused by the SARS-CoV-2 virus is characterized by significant and unpredictable heterogeneity in symptoms that remains poorly understood. Methods Transcriptome and single cell transcriptome of COVID19 lung were integrated with deeplearning analysis of MHC...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-021-02965-5 |