An essential role of the mouse synapse-associated protein Syap1 in circuits for spontaneous motor activity and rotarod balance

An essential role of the mouse synapse-associated protein Syap1 in circuits for spontaneous motor activity and rotarod balance

Synapse-associated protein 1 (Syap1) is the mammalian homologue of synapse-associated protein of 47 kDa (Sap47) in Drosophila. Genetic deletion of Sap47 leads to deficiencies in short-term plasticity and associative memory processing in flies. In mice, Syap1 is prominently expressed in the nervous s...

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Bibliographic Details
Main Authors: Cora R. von Collenberg, Dominique Schmitt, Thomas Rülicke, Michael Sendtner, Robert Blum, Erich Buchner
Format: Article
Language:English
Published: The Company of Biologists 2019-06-01
Series:Biology Open
Subjects:
Syap1 knockout
Motor behaviour
Associative learning
Fear conditioning
Object recognition
Online Access:http://bio.biologists.org/content/8/6/bio042366

Internet

http://bio.biologists.org/content/8/6/bio042366

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