KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring

KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring

Kinesin super family protein 2A (KIF2A), an ATP-dependent microtubule (MT) destabilizer, regulates cell migration, axon elongation, and pruning in the developing nervous system. KIF2A mutations have recently been identified in patients with malformed cortical development. However, postnatal KIF2A is...

Full description

Bibliographic Details
Main Authors: Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G Chaudhary, Mohammed H Al-Qahtani, Nobutaka Hirokawa
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
KIF2A
dentate granule cell
postnatal hippocampal wiring
axon-dendrite determination
temporal lobe epilepsy
Online Access:https://elifesciences.org/articles/30935

Internet

https://elifesciences.org/articles/30935

Similar Items