DCC Expression by Neurons Regulates Synaptic Plasticity in the Adult Brain

DCC Expression by Neurons Regulates Synaptic Plasticity in the Adult Brain

The transmembrane protein deleted in colorectal cancer (DCC) and its ligand, netrin-1, regulate synaptogenesis during development, but their function in the mature central nervous system is unknown. Given that DCC promotes cell-cell adhesion, is expressed by neurons, and activates proteins that sig...

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Bibliographic Details
Main Authors: Katherine E. Horn, Stephen D. Glasgow, Delphine Gobert, Sarah-Jane Bull, Tamarah Luk, Jacklyn Girgis, Marie-Eve Tremblay, Danielle McEachern, Jean-François Bouchard, Michael Haber, Edith Hamel, Paul Krimpenfort, Keith K. Murai, Anton Berns, Guy Doucet, C. Andrew Chapman, Edward S. Ruthazer, Timothy E. Kennedy
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712004299

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http://www.sciencedirect.com/science/article/pii/S2211124712004299

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