DCC Expression by Neurons Regulates Synaptic Plasticity in the Adult Brain

The transmembrane protein deleted in colorectal cancer (DCC) and its ligand, netrin-1, regulate synaptogenesis during development, but their function in the mature central nervous system is unknown. Given that DCC promotes cell-cell adhesion, is expressed by neurons, and activates proteins that sig...

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Bibliographic Details
Main Authors: Katherine E. Horn, Stephen D. Glasgow, Delphine Gobert, Sarah-Jane Bull, Tamarah Luk, Jacklyn Girgis, Marie-Eve Tremblay, Danielle McEachern, Jean-François Bouchard, Michael Haber, Edith Hamel, Paul Krimpenfort, Keith K. Murai, Anton Berns, Guy Doucet, C. Andrew Chapman, Edward S. Ruthazer, Timothy E. Kennedy
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712004299

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