Diacylglycerol-evoked activation of PKC and PKD isoforms in regulation of glucose and lipid metabolism: a review

Diacylglycerol-evoked activation of PKC and PKD isoforms in regulation of glucose and lipid metabolism: a review

Abstract Protein kinase C (PKC) and Protein kinase D (PKD) isoforms can sense diacylglycerol (DAG) generated in the different cellular compartments in various physiological processes. DAG accumulates in multiple organs of the obese subjects, which leads to the disruption of metabolic homeostasis and...

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Bibliographic Details
Main Authors: Katarzyna Kolczynska, Angel Loza-Valdes, Izabela Hawro, Grzegorz Sumara
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Lipids in Health and Disease
Subjects:
Diacylglycerol (DAG)
PKC
PKD
Metabolism
Insulin signaling
Online Access:http://link.springer.com/article/10.1186/s12944-020-01286-8

Internet

http://link.springer.com/article/10.1186/s12944-020-01286-8

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