Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency

Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency

Stem cell plasticity is crucial for early embryo development and the differentiation of stem cells. Here, the authors show that the extracellular protein Cripto sustains mouse ESC self-renewal and maintains mouse EpiSC as well as human ESC pluripotency and controls the metabolic reprogramming in ESC...

Full description

Bibliographic Details
Main Authors: Alessandro Fiorenzano, Emilia Pascale, Cristina D'Aniello, Dario Acampora, Cecilia Bassalert, Francesco Russo, Gennaro Andolfi, Mauro Biffoni, Federica Francescangeli, Ann Zeuner, Claudia Angelini, Claire Chazaud, Eduardo J. Patriarca, Annalisa Fico, Gabriella Minchiotti
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12589

Internet

https://doi.org/10.1038/ncomms12589

Similar Items