Transit through the flea vector induces a pretransmission innate immunity resistance phenotype in Yersinia pestis.

Yersinia pestis, the agent of plague, is transmitted to mammals by infected fleas. Y. pestis exhibits a distinct life stage in the flea, where it grows in the form of a cohesive biofilm that promotes transmission. After transmission, the temperature shift to 37 degrees C induces many known virulence...

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Bibliographic Details
Main Authors: Viveka Vadyvaloo, Clayton Jarrett, Daniel E Sturdevant, Florent Sebbane, B Joseph Hinnebusch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2829055?pdf=render