Oral Administration of <i>Porphyromonas gingivalis</i>, a Major Pathogen of Chronic Periodontitis, Promotes Resistance to Paclitaxel in Mouse Xenografts of Oral Squamous Cell Carcinoma

Oral Administration of <i>Porphyromonas gingivalis</i>, a Major Pathogen of Chronic Periodontitis, Promotes Resistance to Paclitaxel in Mouse Xenografts of Oral Squamous Cell Carcinoma

Chemotherapy is not a first-line therapy for oral squamous cell carcinoma (OSCC), which is the most common type of oral cancer, because most OSCC shows resistance to chemotherapeutic reagents. Inflammatory signals are suggested to be associated with chemoresistance as well as carcinogenesis in many...

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Bibliographic Details
Main Authors: Jae Min Song, Bok Hee Woo, Ji Hye Lee, Sanggyeong Yoon, Youngseuk Cho, Yong-Deok Kim, Hae Ryoun Park
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Porphyromonas gingivalis</i>
chronic periodontitis
oral cancer
chemoresistance
paclitaxel
cytokine
ibuprofen
Online Access:https://www.mdpi.com/1422-0067/20/10/2494

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https://www.mdpi.com/1422-0067/20/10/2494

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