Polymorphisms in the Gene Encoding Caspase 8 May Predict the Response to First-Line Platinum-Based Chemotherapy in Locally Advanced or Advanced Non-Small-Cell Lung Cancer

Polymorphisms in the Gene Encoding Caspase 8 May Predict the Response to First-Line Platinum-Based Chemotherapy in Locally Advanced or Advanced Non-Small-Cell Lung Cancer

Caspase 8 is a protein involved in the process of cell apoptosis, which may affect the efficacy of anti-cancer treatment. The aim of our study was to determine the impact of polymorphisms in the <i>CASP-8 </i>gene encoding caspase 8 on the prognosis in non-small-cell lung cancer (NSCLC)....

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Bibliographic Details
Main Authors: Michał Szczyrek, Radosław Mlak, Aneta Szudy-Szczyrek, Karolina Kędziora, Teresa Małecka-Massalska, Paweł Krawczyk, Janusz Milanowski
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Journal of Clinical Medicine
Subjects:
caspase 8
<i>CASP-8</i>
NSCLC
platinum
polymorphism
Online Access:https://www.mdpi.com/2077-0383/10/5/1126

Internet

https://www.mdpi.com/2077-0383/10/5/1126

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