Refining ensembles of predicted gene regulatory networks based on characteristic interaction sets.

Different ensemble voting approaches have been successfully applied for reverse-engineering of gene regulatory networks. They are based on the assumption that a good approximation of true network structure can be derived by considering the frequencies of individual interactions in a large number of...

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Bibliographic Details
Main Authors: Lukas Windhager, Jonas Zierer, Robert Küffner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3911903?pdf=render