PIASgamma is required for faithful chromosome segregation in human cells.

PIASgamma is required for faithful chromosome segregation in human cells.

BACKGROUND:The precision of the metaphase-anaphase transition ensures stable genetic inheritance. The spindle checkpoint blocks anaphase onset until the last chromosome biorients at metaphase plate, then the bonds between sister chromatids are removed and disjoined chromatids segregate to the spindl...

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Bibliographic Details
Main Authors: Laura A Díaz-Martínez, Juan F Giménez-Abián, Yoshiaki Azuma, Vincent Guacci, Gonzalo Giménez-Martín, Lorene M Lanier, Duncan J Clarke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762334?pdf=render

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http://europepmc.org/articles/PMC1762334?pdf=render

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