Myeloperoxidase-Related Chlorination Activity Is Positively Associated with Circulating Ceruloplasmin in Chronic Heart Failure Patients: Relationship with Neurohormonal, Inflammatory, and Nutritional Parameters

Rationale. Heart failure (HF) is accompanied by the development of an imbalance between oxygen- and nitric oxide-derived free radical production leading to protein nitration. Both chlorinating and peroxidase cycle of Myeloperoxidase (MPO) contribute to oxidative and nitrosative stress and are involv...

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Main Authors: Aderville Cabassi, Simone Maurizio Binno, Stefano Tedeschi, Gallia Graiani, Cinzia Galizia, Michele Bianconcini, Pietro Coghi, Federica Fellini, Livia Ruffini, Paolo Govoni, Massimo Piepoli, Stefano Perlini, Giuseppe Regolisti, Enrico Fiaccadori
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/691693