Extreme high prevalence of a defective mannose-binding lectin (MBL2) genotype in native South American West Andean populations.

Extreme high prevalence of a defective mannose-binding lectin (MBL2) genotype in native South American West Andean populations.

Mannose-binding lectin (MBL) is one of the five recognition molecules in the lectin complement pathway. Common variant alleles in the promoter and structural regions of the human MBL gene (MBL2) influence the stability and serum concentration of the protein. Epidemiological studies have shown that M...

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Bibliographic Details
Main Authors: José Raul Sandoval, Hans O Madsen, Gianfranco De Stefano, Jaime Descailleaux-Dulanto, Margarita Velazquez-Reinoso, Cesar Ñique, Ricardo Fujita, Peter Garred
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4196846?pdf=render

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http://europepmc.org/articles/PMC4196846?pdf=render

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